5-HTP Supreme™ is a synergistic formula of 5-hydroxytryptophan (100 mg) and vitamin B6 (20 mg) per serving for supporting overall neurotransmitter metabolism by providing precursors of serotonin. 5-HTP readily enters the blood–brain barrier; however, conversion into serotonin requires the cofactor vitamin B6, which is included in this formula. 5-HTP Supreme™ may be used during the day to support a healthy mood and normal appetite, or it may be used at bedtime to support sleep.* This formula can be used in place of 5-HTP Synergy™ when higher doses of 5-HTP are recommended.

††An IPSOS 2023 survey among US functional medicine practitioners, in an average month, Designs for Health is their personally most trusted practitioner supplement brand, meaning a brand that is sold by healthcare practitioners in their office.

††An Ipsos 2023 study among a random sample of 160 functional medicine practitioners including Doctor's of Osteopathic Medicine, Pharmacists, Acupuncturists, Athletic Trainers, Personal Trainers, Fitness Trainer/Coaches, Chiropractors, Integrative Medicine Specialists, Naturopathic Doctor, Homeopaths, Medical Doctors, Physical Therapists, Nurse Practitioner/Physician Assistants, Registered Nurses, Nutritionists, Massage Therapists, Occupational Therapists and Dieticians that are aware of Designs for Health and recommend supplements to their patients.